Is Marriage a Risk Factor for Allergic Rhinitis? | OMICS International
Change the date range, chart type and compare Astrazeneca PLC against other companies. AstraZeneca sells older asthma, rhinitis drugs for $ million. Svetozara Markovica 69, Kragujevac, , Serbia. [email protected] Current treatment for children with asthma and allergic rhinitis include This article presents insights into the up-to-date understanding of. Allergic rhinitis (AR) is associated with various developmental issues that dates of medical treatment, International Classification of Diseases.
Combination of levocetirizine with montelukast has shown a significant improvement in patients with allergic rhinitis. There was a significant improvement in both daytime and nighttime symptoms in patients on combination therapy as compared to placebo and giving both the drugs as monotherapy [ 15 - 17 ].
There are only limited studies available for the effect of combination therapy of montelukast and levocetirizine on the Indian population. Hence, this study was designed to assess the efficacy of montelukast with levocetirizine as treatment for allergic rhinitis in Indian population.
Materials and Methods Study design This prospective, randomized, open, parallel group study with a 2 week run-in period and a 6 week treatment period was conducted between July to April at the outpatient department of Gian Sagar Medical College and Hospital, District Patiala.
Clinic visits were scheduled at screening visit 1after a 14 day run-in period visit 2after every 2 weeks of treatment according to randomization for 6 weeks visit 3,4,5. During the run-in period patients received only Tripolidine HCl and Pseudoephedrine HCl as needed to relieve symptoms.
During the randomization period patients were randomly allocated using random number table to receive Tab Levocetirizine 5mg and Montelukast 10mg in the treatment group or levocetirizine 5mg in control group once daily at bed time for 6 weeks.
The medical compliance was determined from the returned tablet count. A physical examination for nasal secretion and turbinate swelling was also done at each visit. The study protocol and informed consent were reviewed and approved by Institutional Ethics Committee of Gian Sagar Medical College and Hospital before the study initiation and written informed consent was obtained from each patient prior to enrolment in the study.
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Patients Adults years old of both sexes with a clinical history of perennial allergic rhinitis for at least 1 year, non-smokers, who could read and understand the protocol middle level education and were willing to give written consent, were eligible for study. Study exclusion included pregnancy or lactation, any polyposis or infectious pathology during physical examination, alcohol or illicit drug, asthma, major surgery within 4 weeks, upper respiratory tract infection within 3 weeks prior to study.
Medications that were prohibited prior to the study included: Daily rhinitis diary card Recorded on the daily diary card, the allergic rhinitis and conjunctivitis symptoms were assessed on a 4-point scale 0 to 3 for both daytime diary card completed in the evening and nighttime diary card completed on awakening.
The daytime nasal rhinorrhea, sneezing, itching and congestionnight time nasal nasal congestion upon awakening, difficulty going to sleep and night time awakening and eye tearing, itching, redness and puffing symptoms and their rating were described to every patient by the same technician.
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The ratings of the symptom were: Shad and Sircar, presented in cases report of four patients had experienced postcoital exacerbation of asthma and allergic rhinitis in India.
Here in our study we have reported 11 cases 7 females and 4 males having postcoital exacerbation of allergic symptoms. This postcoital rhinitis or honeymoon rhinitis is most probably due to emotional excitement or autonomic parasympathetic over activity with cholinergic release of mast cell mediators.
We have found that 6 cases from 11 cases having positive postcoital phenomenon, having positive family history of AR, and positive postcoital AR as well. Spring was found the most common month to flare the postcoital attacks. Only 2 patients had positive consanguous marriage and positive postcoital AR. However, we would like to stress that postcoital allergic rhinitis may be easily overlooked due to patient embarrassment or lack of awareness specially in our society, and hence it needs more detailed study to understand more about the pathophysiology and mechanisms which will lead to proper management and actual and adequate knowing of the prevalence of the disorder.
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Conclusion Allergic Rhinitis prevalence in Eastern province of Saudi Arabia is significantly higher in the rural areas than urban areas. Intermittent allergic rhinitis is the predominant type, and of the mild form.
The main trigger factors and risk factors are genetic factors like family history, and environmental factors like pollen and smoking. It is more common in winter, at the early morning time. Eighteen percent of cases experienced postcoital exacerbation of allergic rhinitis attacks. However, vasomotor rhinitis might be a possible diagnosis if the patient age is above 35 with no family history of allergies.
Acknowledgement We would like to thank Anwar Sattam, medical student for her helpful work in datacollection.
Sujichim, hand acupuncture A woman receiving fire cupping in China. Effectiveness Acupuncture has been researched extensively; as ofthere were almost 1, randomized controlled trials on PubMed with "acupuncture" in the title. The results of reviews of reviews of acupuncture's effectiveness, however, have been inconclusive. In other words, 'sham' or 'placebo' acupuncture generally produces the same effects as 'real' acupuncture and, in some cases, does better.
This study also found that selective reporting of results and changing outcome measures to obtain statistically significant results was common in this literature.
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The same review noted that "It is difficult to draw conclusion [sic] because the included studies have a high risk of bias and imprecision. The same review found that the strength of the evidence for both conditions was low to moderate.
A overview of systematic reviews found insufficient evidence to suggest that acupuncture is effective for surgical or post-operative pain.